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Gupta, Y. K.
- Synthesis and Antimicrobial Activity of New 4-Thiazolidinone Derivatives Containing 2-Amino-6-Ethoxybenzothiazole
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Authors
Y. K. Gupta
1,
S. C. Agarwal
2
Affiliations
1 Department of Chemistry, B K Birla Institute of Engineering and Technology, Pilani, Jhunjhunu, Rajasthan-333031, IN
2 Department of Chemistry, Agra College, Agra, U.P, IN
1 Department of Chemistry, B K Birla Institute of Engineering and Technology, Pilani, Jhunjhunu, Rajasthan-333031, IN
2 Department of Chemistry, Agra College, Agra, U.P, IN
Source
Asian Journal of Research in Chemistry, Vol 4, No 12 (2011), Pagination: 1945-1952Abstract
A novel series of Schiff bases 5a-j and 4-thiazolidinones 6a-j have been prepared from the building blocks 2-chloro pyridine-3-carboxylic acid [1] and 2-amino-6-ethoxy-benzothiazole [2]. All of the synthesized compounds have been confirmed by elemental analyses, IR, 1H NMR and 13C NMR spectral data. These newly synthesized compounds were screened for their antimicrobial activity. Variable and modest activity was observed against the investigated strains of bacteria and fungi, however, compound 6h revealed significant antibacterial activity against Escherichia coli. Compounds 1, 2, 3, 5c, 5g and 5h, on the other hand, revealed potent antifungal activity against Candida albicans compared to the reference drug greseofulvinKeywords
Schiff Bases, 4-Thiazolidinones, 2-Chloro Pyridine-3-Carboxylic Acid, 2-Amino-6-Ethoxybenzothiazole, Antimicrobial Activity.
- Solubility of Some Pyrimidine Derivatives in Methyl-Alcohol at Different Temperatures
Abstract Views :157 |
PDF Views:3
Authors
Affiliations
1 School of Applied Sciences, Singhania University, Pacheri Bari, Jhunjhunu (Raj.), IN
2 Department of Chemistry, Agra College, Agra, U.P, IN
3 Department of Chemistry, B K Birla Institute of Engineering and Technology, Pilani, Rajasthan, IN
1 School of Applied Sciences, Singhania University, Pacheri Bari, Jhunjhunu (Raj.), IN
2 Department of Chemistry, Agra College, Agra, U.P, IN
3 Department of Chemistry, B K Birla Institute of Engineering and Technology, Pilani, Rajasthan, IN
Source
Asian Journal of Research in Chemistry, Vol 10, No 2 (2017), Pagination: 186-190Abstract
The solubility of some of Pyrimidine derivatives in methyl alcohol was measured by gravimetrical method at different temperatures (293.15 to 313.15 K) under atmospheric pressure. The solubility data were comprised with temperature by Apelblat equation. Some thermodynamic parameters such as dissolution enthalpy, and Gibbs' free energy of dissolution and entropy were evaluated from solubility data.Keywords
Pyrimidine Derivatives, Solubility Data and Thermodynamic Parameters.- Synthesis of Some Chalcone and their Heterocyclic Derivatives as Potential Antimicrobial Agents:A Review
Abstract Views :187 |
PDF Views:3
Authors
Affiliations
1 School of Applied Sciences Singhania University, Pacheri Bari, Jhunjhunu (Raj.), IN
2 Department of Chemistry, Agra College, Agra, U.P, IN
3 Department of Chemistry, B K Birla Institute of Engineering and Technology, Pilani, Rajasthan, IN
1 School of Applied Sciences Singhania University, Pacheri Bari, Jhunjhunu (Raj.), IN
2 Department of Chemistry, Agra College, Agra, U.P, IN
3 Department of Chemistry, B K Birla Institute of Engineering and Technology, Pilani, Rajasthan, IN